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What Is JULAINE? Everything You Need to Know

The Injectable Treatment That Improves Skin Quality Over Time

JULÄINET smoothens your wrinkles and tightens

Orchard House is thrilled to be one of the few select clinics in the UK offering the revolutionary Julaine treatment!

(From February 2026)

You’ve probably seen Julaine popping up all over the press lately… and for good reason!

In Aesthetic Medicine, we are moving away from simply treating visible signs of ageing and towards addressing the underlying biological processes that cause skin to age.

Julaine represents a genuine shift in how we approach skin rejuvenation.

What Is Julaine?

Julaine is an advanced injectable treatment based on poly-L-lactic acid (PLLA). However, Julaine is more than just a 'collagen stimulator' it is a true skin regenerator. It doesn’t simply make the skin appear more youthful — it helps restore skin health from within.

Julaine is ideal for patients seeking lift, tightening, and improved skin texture -without adding unnatural looking volume. Creating a radiant refreshed yet naturally radiant look.

How does Julaine work?

To understand how Julaine works, firstly lets look at what happens to our skin as we age.....
From the age of 25, our skin’s natural production of collagen begins to slow and continues to decrease by around 1–2 per cent each year. This gradual loss of collagen results in visible signs of ageing, including reduced elasticity and volume, fine lines and wrinkles, and a tired, sagging appearance.

Understanding “Inflammageing”

Skin ageing is no longer understood as a 'passive' process. Research shows that ageing skin is driven by a process known as inflammageing — a state of chronic, low-grade inflammation that slowly damages skin structure over time.

This inflammation is influenced by both:

Intrinsic factors

  • Genetics

  • Hormonal changes

  • Natural metabolic ageing

Extrinsic factors

  • UV exposure

  • Pollution

  • Stress

  • Poor sleep

  • Smoking

  • Nutrition

Together, these factors create repeated inflammatory stress within the skin. Over time, this disrupts collagen production, weakens elasticity, causes  pigmentation and uneven skin tone, and accelerates visible ageing.

Simply adding volume or repeatedly stimulating collagen without addressing this inflammatory environment can sometimes worsen the problem rather than solve it.

To truly improve skin quality, we need controlled, intelligent stimulation, not aggressive or excessive intervention.

Patient showing nasolabial folds results at 2 months after 1st injection of HCP

Frequently Asked Questions about Julaine

What is Julaine? 

Julaine is an advanced skin-stimulating treatment designed to improve skin quality, firmness, and strength over time.

It is classed as a "dermal bio-activator." 

Unlike fillers, 

Julaine does not add volume or change facial shape. Instead, it works by encouraging your skin to rebuild its own structure naturally, leading to healthier, more resilient skin.

What makes Julaine different?

It has been carefully designed to work with your body, not against it. Its intelligent formulation:

  • Encourages healthy collagen production

  • Supports skin repair rather than inflammation

  • Works gradually for natural-looking results

What results will I see from Julaine treatment?

Results develop slowly over several weeks as your skin produces new collagen. Most patients notice:

  • Improved firmness and elasticity

  • Smoother skin texture

  • A healthier, more refreshed appearance

  • Because results build naturally, people often say you look well, not done.

How Is Juliane Different from Sculptra /Traditional PLLA?

While traditional PLLA products stimulate collagen, their results can sometimes be unpredictable. This is often due to how the body’s immune system reacts to the PLLA particles.

However, the PLLA particles in Julaine have been intelligently designed.

Traditional PLLA vs Julaine

Traditional PLLA Julaine PLLA
Can trigger prolonged inflammation Designed to support resolution of inflammation
Variable collagen quality Encourages healthier collagen regeneration
Higher risk of nodules in some patients Lower risk due to advanced particle engineering
Results can be unpredictable More controlled, consistent outcomes

Julaine represents a new generation of skin biostimulation, focusing on skin health rather than just collagen quantity.

Who is Julaine treatment ideal for?

  • If you are seeking lift, tightening, and improved skin texture and quality without added "volume"
  • Prevention from skin ageing
  • Sundamaged and lax skin (as part of a holistic treatment program)
  • Where Dermal filler/other treatments are not suitable

How many treatments of Julaine will I need?

This will be discussed with you during your consultation. Typically, a protocol of three sessions spaced 4-6 weeks apart is needed for optimum results.

When will I see results?

Results are typically seen six weeks after the first session and gradually improve.

How long does Julaine last?

Results last for up to two years, with patients requiring top ups as desired for maintenance.

How much is Julaine treatment?

Julaine is a very personalised treatment. Cost is dependent on the amount of product needed and over how many sessions. This is discussed with you during your consultation.

Ready to improve your skin quality from within?

Book a personalised Juliane consultation and discover whether advanced PLLA skin regeneration is right for you.

Book Consultation   or  Read More

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JULÄINE in the Press 2026

Images on this page from Nordberg Medical (JULÄINE)

Julaine in country and town house articleJulaine in Country & Town House 2026

Julaine PLLA